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Blog Posts (3)

  • Psilocybin produces substantial and sustained decreases in depression & anxiety in Cancer patients

    Mystical-type psilocybin experience on session day mediated the effect of psilocybin dose on therapeutic

  • Long-term follow-up of psilocybin-facilitated smoking cessation

    Abstract Background: A recent open-label pilot study (N = 15) found that two to three moderate to high doses (20 and 30 mg/70 kg) of the serotonin 2A receptor agonist, psilocybin, in combination with cognitive behavioral therapy (CBT) for smoking cessation, resulted in substantially higher 6-month smoking abstinence rates than are typically observed with other medications or CBT alone. Objectives: To assess long-term effects of a psilocybin-facilitated smoking cessation program at ≥12 months after psilocybin administration. Methods: The present report describes biologically verified smoking abstinence outcomes of the previous pilot study at ≥12 months, and related data on subjective effects of psilocybin. Results: All 15 participants completed a 12-month follow-up, and 12 (80%) returned for a long-term (≥16 months) follow-up, with a mean interval of 30 months (range = 16-57 months) between target-quit date (i.e., first psilocybin session) and long-term follow-up. At 12-month follow-up, 10 participants (67%) were confirmed as smoking abstinent. At long-term follow-up, nine participants (60%) were confirmed as smoking abstinent. At 12-month follow-up 13 participants (86.7%) rated their psilocybin experiences among the five most personally meaningful and spiritually significant experiences of their lives. Conclusion: These results suggest that in the context of a structured treatment program, psilocybin holds considerable promise in promoting long-term smoking abstinence. The present study adds to recent and historical evidence suggesting high success rates when using classic psychedelics in the treatment of addiction. Further research investigating psilocybin-facilitated treatment of substance use disorders is warranted. [FULL TEXT]

  • Rapid and sustained symptom reduction following psilocybin treatment

    The psilocybin-induced mystical experience mediated the therapeutic effect of psilocybin on anxiety and

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  • ZenSpore | Unites States | Mushroom Research Library

    Research Institute Date: December 2016 Keywords: Psilocybin, anxiety, cancer, depression, hallucinogen, mystical Mushroom Research Institute Date: December 2016 Keywords: Psilocybin, anxiety, cancer, depression, mystical through the 1-month follow-up Mushroom Research Institute Date: date Keywords: Hallucinogen, addiction, mystical

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