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Objective To investigate the effect of psilocybin therapy in patients with MDD. Participants This randomized, waiting list–controlled clinical trial was conducted at the Center for Psychedelic Conclusions and Relevance Findings suggest that psilocybin with therapy is efficacious in treating MDD

June 2019 ABSTRACT The main psychedelic component of magic mushrooms is psilocybin, which shows promise Psychedelic effects are believed to emerge through stimulation of serotonin 2A receptors (5-HT2ARs) by We here report for the first time the relationship between intensity of psychedelic effects, cerebral Subjective psychedelic intensity and plasma psilocin levels were measured during the scans. studies, psilocin time-concentration curves varied but psilocin levels were closely associated with psychedelic

Results Neuroticism scores significantly decreased while Extraversion increased following psilocybin therapy Conclusion Our observation of changes in personality measures after psilocybin therapy was mostly consistent although the pronounced increases in Extraversion and Openness might constitute an effect more specific to psychedelic therapy.

disorder, mdd, psychedelic integration therapy, p.i.t., p.a.t. Article Name: Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder: Description: In this participants with major depressive disorder, participants who received immediate psilocybin-assisted therapy Mushroom Research Institute Date: September 2021 Keywords: antidepressant therapy, depression, psilocin Article Name: Effects of psilocybin therapy on personality structure Description: Twenty patients with

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